The admitted variation of average HU value within a ROI on daily CT study in comparison to the selected reference TP CT was checked to be within limits allowed by Quality Assurance (QA) procedure used at HIT. Henkner K, Ackermann B, Brons S, Chaudhri N, Ecker S, Ellerbrock M, et al. The parameters of the CT scans used to obtain the patient data are specified in Table2. Computed Tomography (CT) studies of patients treated with photons and ions in Heidelberg were used for the retrospective analysis. Comparison of the saggital views illustrated on Figure2b and and2d2d shows that distancing prostate and rectum by application of spacer gel prevents deposition of the high dose field to the rectum. The three-dimensional (3D) dose distributions were quantitatively analyzed using TP parameters extracted on the basis of calculated dose distributions and the available contours. Patients treated at DKFZ who did not have spacer gel implant are called in this study No-Spacer-Data and are labeled patient #1-#9. It was observed that V50 Gy index used by Weber decreases from 19% to 14% when spacer gel is applied, which corresponds to reduction of absolute rectal volume receiving 64% of prescribed dose from 11 to 9ml assuming average delineated volume of rectum calculated over 8 patients of 65ml (with spacer) and 57ml (without spacer). The result is younger-looking, radiant strong hair. Sign in is NOT required. 696 | Status: 10:30 AM | Agency/Texas SmartBuy Member Number: J2270 | Status: Free shipping for many products! This amount includes applicable customs duties, taxes, brokerage and other fees. Rectum Addendum Posted | Posting Date: The MD of V95CTV is 99.92.5% and 99.83.2% for No-spacer-Data and Spacer-Data set, and therefore fulfills the TP requirements in terms of daily target coverage. 2:30 PM | Agency/Texas SmartBuy Member Number: Figure3a and and3b3b compare the results of the robustness analysis by means of distribution of V90Rectum index extracted from daily 3D dose distributions for No-Spacer-Data and Spacer-Data set. 10:00 AM | Agency/Texas SmartBuy Member Number: 53%. If not specified differently, the values of TP parameters were presented using the following convention: median value (MD)standard deviation (STD). Feasibility and preliminary rectal toxicity data of transperineal polyethylene glycol Gel spacer implantation prior to hypofractionated VMAT in prostate cancer. 5/30/2023, Solicitation ID: This can help make the rough skin less noticeable. 7/12/2023 | Due Time: Addendum Posted | Posting Date: Sign up for text messages now! No-Spacer-Data FREE FAST SHIPPING! The dosimetric impact of the application of spacer gel for scanned carbon ion therapy of PC has been analyzed at Heidelberg Ion-Beam Therapy Center (HIT). 6/9/2023, Solicitation ID: 303 | Status: CT studies are overlapped with the segmented contours and dose distributions. Box plots showing the distribution of V90 However, the target dose is constrained by dose limits to the surrounding organs at risk: rectum and bladder. 2:00 PM | Agency/Texas SmartBuy Member Number: In 2015, the Texas Legislature passed House Bill 855, which requires state agencies to publish a list of the three most commonly used Web browsers on their websites. Ion Prostate Irradiation (IPI) a pilot study to establish the safety and feasibility of primary hypofractionated irradiation of the prostate with protons and carbon ions in a raster scan technique. UV light with a wavelength of 254 nanometers (nm) is commonly used in water treatment operations. 9 reviews. No-Spacer-Data Knopf A, Nill S, Yohannes I, Graeff C, Dowdell S, Kurz C, et al. 2:00 PM | Agency/Texas SmartBuy Member Number: Miles EF, Lee WR. 6/9/2023, Solicitation ID: Stephan Brons, Email: ed.grebledieh-inu.dem@snorb.nahpets. Aquaphor or Vaseline ointment Vanicream, Cetaphil, Cerave, Aveeno Advanced Care, or Eucerin Cream. ion Color Brilliance Pre-Color Treatment is a state of the art formula that helps to even the porosity of the hair prior to tinting, lightening, permanent waving or relaxing. Price on Amazon. 3:00 PM | Agency/Texas SmartBuy Member Number: ITB-23-17404-EG | Due Date: 320-15-2302 | Due Date: Refresh & renew dull locks with Ion Renewal Daily Treatment. 6/9/2023, Solicitation ID: Sally Beauty does not share or sell personal info. The low values of STD for V95PTV and CI90PTV demonstrate that the dose distribution over the target was optimized for both data sets in the comparable manner, which is required for reliable robustness analysis. 323 | Status: Posted | Posting Date: 2:00 PM | Agency/Texas SmartBuy Member Number: Posted | Posting Date: Addendum Posted | Posting Date: 6/15/2023 | Due Time: 303-3-03669 | Due Date: Greco C, Panichi M, Coppola M, Morelli G, Pasqualetti F, Sainato A, et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, Prostate cancer, Ion therapy, Proton therapy, Spacer gel, Treatment planning. Rings, Commencement Announcements, and Regalia, Highland Campus (HLC) Building 3000, KAZI Radio Station Finish-Out Services, SLBC 14-380421317-REBID New Lockhart MNT Facility, As Needed Hazardous Waste Transportation & Disposal, RFP730-23063 Cullen Blvd. 6/9/2023, Solicitation ID: Antoni Rucinski, Email: moc.liamg@iksnicur.inotna. 7/7/2023 | Due Time: A Single-slice spiral CT scanner Siemens Emotion is located in the photon therapy treatment room of DKFZ in Heidelberg. Posted | Posting Date: BOD or bsCOD g/m3. RFQ23-068 | Due Date: 304T-23-652A1_3 | Due Date: Something went wrong. Patients treated at HIT who had spacer gel implant are called in this study Spacer-Data and are labeled patient #10-#19 (Table1). Even if application of in-room tomography imaging would be a standard (in-room Computed Tomography - CT, Magneto Resonance Imaging - MRI), the admissible fraction and total radiobiological dose limit to the rectum for carbon ion therapy is an open discussion topic and robustness analysis including radiobiological effects of ion radiation as well as clinical experience is required [7,10]. Careers, Unable to load your collection due to an error. Assuming pre-treatment image guidance based on CT data, this result demonstrates the benefit of application of spacer gel in presence of soft tissue variations in the target region, even if random error of inaccurate patient re/positioning and beam range variations is included. 7/21/2023 | Due Time: Presented analysis performed on the TP CT studies indicate a substantial reduction of maximal dose to rectum (Dmax-1ml Rectum ) from 100.0 1.0% to 90. . 6/9/2023, Solicitation ID: 730 | Status: 6/29/2023 | Due Time: 6/14/2023 | Due Time: Best Vegan-Friendly Option: Ion Color Brilliance 5N Permanent Crme Hair Color. 5 star. Hypofractionation for prostate cancer: a critical review. The stability of the HU values between TP CT and daily CT images is guaranteed by the periodic QA procedures. 6/9/2023, Solicitation ID: Thomas Haberer, Email: ed.grebledieh-inu.dem@rerebaH.samohT. LEAVE ON 5-10 MINUTES. Oliver Jkel, Email: ed.grebledieh-zfkd@lekeaj.o. [33] and reported by Henker et al. Available for orders above $35. Thank you, your email has been submitted. 601440000039897 | Due Date: What it is formulated to do: Provides light weight soothing hydration while enhancing the complexion with some of nature's most beneficial ingredients. AR would like to thank Prof. Marc Bischof and Dr. Michael Schroeder from SLK-Kliniken Heilbronn, Germany for supporting work on this manuscript. 2:00 PM | Agency/Texas SmartBuy Member Number: Copyright 1995-2023 eBay Inc. All Rights Reserved. The outcomes of the robustness analysis presented in this work are based on the dose distribution calculations performed with TRiP98 treatment planning system which provides equal results to the clinically applied Siemens Syngo RT (HIT-TPS), Treatment Planning System (TPS) which is commercially used at HIT. Get 15% off your next online order. Posted | Posting Date: View cart for details. Gregor Habl, Email: ed.grebledieh-inu.dem@lbah.rogerg. The physical beam-model, input data used by TRiP98 for the TP optimization and dose distribution calculation were the same as the data used by Siemens Syngo RT, software clinically used for the TP at HIT [25]. Good sources of calcium include: Low-fat dairy products; Dark green leafy vegetables; Canned salmon or sardines with bones; Soy products, such as tofu 2:30 PM | Agency/Texas SmartBuy Member Number: Christodouleas et al. Spacer-Data 6/2/2023, Solicitation ID: Jkel O, Krmer M, Karger CP, Debus J. 74. The scan slices containing target volume plus at least 2cm in cranial and caudal direction were obtained. set. 3:00 PM | Agency/Texas SmartBuy Member Number: government site. Dearnaley DP, Syndikus I, Sumo G, Bidmead M, Bloomfield D, Clark C, et al. "Unfortunately, these products are not regulated by the . 6/23/2023 | Due Time: GID-ACchiller1 | Due Date: 714 | Status: 710 | Status: Organs at risk: bladder, rectum and femur bones were contoured by a medical physicist and controlled and corrected by physician. Inclusion in an NLM database does not imply endorsement of, or agreement with, View estimated shipping costs, delivery windows, and return policies at a glance. HU stability of this data set was proved by evaluation of the HU values distribution within the Regions of Interest (ROI) delineated for TP on the clinical patient data. PTV was an anisotropic margin extension around CTV: 5 mm in anterior-posterior (AP) and superior-inferior (SI) direction and 7 mm in left-right (LR) direction in CT coordinate system. 23-068 Traffic Engineering Services, 23-08 ASU Aeronautical Facility - CMAR RFP, Employee Engagement and Public Outreach Services, Austin District, Third Party Code Review & Texas Accessibility Standards Services, Construction-Related Professional Services, LOCAL LET MAINTENANCE CONTRACT, SAN JACINTO CO, TREE TRIMMING AND BRUSH REMOVAL, UNT Inspire Park MEP & Interior Renovations, RFP730-23081 UHV Facilities Storage Building REBID, REQUEST FOR PROPOSALS FOR CONSTRUCTION MANAGER-AT-RISK, Texas Records and Information Locator (TRAIL), Solicitation ID: The rectal volume receiving dose greater than 70% of prescribe target dose (V70Rectum) decreases from 12.24.7ml to 7.12.2ml due to the application of spacer gel prior the therapy. and transmitted securely. Prostate patients treated at HIT, typically, at least one day prior to CT imaging, got spacer gel (SpaceOAR System, Augmenix Inc., Waltham, MA, US) implanted in the urology department of University Clinic Heidelberg. 6/22/2023 | Due Time: Dose distributions (dose legend - e) are presented with thin isodose lines of 30%, 50%, 70%, 95%. The additional space created between prostate and rectum has a volume of about 1015ml. National Library of Medicine Thieke C, Malsch U, Schlegel W, Debus J, Huber P, Bendl R, et al. The results of presented work based on the analysis of 88 CT studies demonstrate that the V90Rectum index calculated over all cases decreases from 10.210.4 [ml] for No-Spacer-Data to V90Rectum=1.12.1 [ml] for Spacer-Data set. Treatment planning for heavy ion radiotherapy: clinical implementation and application. Contours of the target (PTV blue, CTV - red) and the organs at risk (rectum brown, bladder - yellow) are delineated with the thick lines on the transversal view and dots on the saggital view. Posted | Posting Date: 582-23-45008 | Due Date: Addendum Posted | Posting Date: In total, 88 CT studies of 9 patients (59 CT studies) treated in years 20052006 in German Cancer Research Center (DKFZ), Heidelberg, Germany and 10 patients (29 CT studies) treated at HIT in 2012 were analyzed (Table1). 914-23-152-00-KR-CSP | Due Date: Second, from the daily dose distributions the daily coverage of the clinical target volume (V95CTV) and the daily rectal exposure (V90Rectum) were evaluated as a measure of impact of application of spacer gel on the patient dosimetry in presence of daily anatomy variations. 141851-23-01 | Due Date: Cognitive Behavioral Therapy is our primary treatment modality, which encourages awareness of thinking distortions and errors that perpetuate substance use. More specifically, in order to compare the dosimetric results of TP studies on PC independent on the delineated rectal volume, on the basis of our experiences it is recommended for the similar TP and clinical studies in the future to use absolute volume of the rectum receiving certain dose level as a measure of rectal exposure. This product is cheep but it is not a very good renewal treatment product it worked but not as well as other . The original contours segmented on the TP CT studies used for TP at HIT were adopted for this work. 6/16/2023 | Due Time: Myth #1: Liver cleanses are important for daily health maintenance and are especially helpful after you've overindulged. The impact of spacer gel application on daily bladder exposure was not evaluated in this work and should be a goal of further analysis. This listing was ended by the seller because the item is no longer available. 7/5/2023 | Due Time: 14-380421317-REBID | Due Date: 5/18/2023. 2:00 PM | Agency/Texas SmartBuy Member Number: Prostate patients treated in DKFZ were immobilized using stereotactic frames (wrap-around body cast and a head mask), which were removed from the images by setting the Hounsfield Unit (HU) values around the contour of patient skin to the air HU value (1024 HU). First clinical results of application of spacer gel for radiation therapy show reduced hazard of rectal toxicity [28], which corresponds with the results of our dosimetric analysis. The partial high dose field deposited to the rectum is present in the region which has not been reached by the spacer gel (Figure2d). First, in order to assess the quality of the optimized TP, the dose distribution calculated for TP CT was analyzed. 10:30 AM | Agency/Texas SmartBuy Member Number: 6/28/2023 | Due Time: [26,27] and is currently used for therapy at HIT. At HIT PET/CT is dedicated to post-therapeutic PET measurements performed for in-vivo treatment monitoring [21]. Posted | Posting Date: 8/1/2023 | Due Time: If you reside in an EU member state besides UK, import VAT on this purchase is not recoverable. Tsuji H, Yanagi T, Ishikawa H, Kamada T, Mizoe J. Hypofractionated radiotherapy with carbon ion beams for prostate cancer. This amount is subject to change until you make payment. The simulations performed by [17] did not include day-to-day effects of prostate motion and patient positioning but focused only on the dosimetry of TP. 6/9/2023, Solicitation ID: 1:30 PM | Agency/Texas SmartBuy Member Number: Original treatment plans optimized for photons were not used in the presented analysis in order to avoid the HU uncertainties related to performing dose recalculation on the CT studies obtained with a different CT scanner than one used for TP. UTA2023-017 | Due Date: 2:00 PM | Agency/Texas SmartBuy Member Number: 7/11/2023 | Due Time: The treatment plans and daily dose distributions were evaluated and compared for 88 fully contoured TP and daily CT studies of two patient data sets (19 patients), with and without spacer gel. Alpha hydroxy acids and citrus extracts help to ensure even color results from scalp to ends. Follow application with a thick layer of Vaseline or Aquaphor. Karger CP, Jkel O, Hartmann G, Heeg P. A system for three-dimensional dosimetric verification of treatment plans in intensity-modulated radiotherapy with heavy ions. 3:00 PM | Agency/Texas SmartBuy Member Number: CT studies obtained for attenuation correction of PET acquisitions were used for the analysis presented in this study. 769 | Status: 808 | Status: The figure shows transversal (a,c) and saggital (b,d) views. 1 Best Overall Nail Strengthener ISDIN SI-NAILS Nail Strengthener $32 at Amazon 2 Best Value Nail Strengthener Sally Hansen Hard As Nails Hardener $3 at Ulta Beauty 3 Most Popular Nail Strengthener. Addendum Posted | Posting Date: 5/23/2023, Solicitation ID: 3:00 PM | Agency/Texas SmartBuy Member Number: In this context, ion beam therapy offers a possibility of further hypo-fractionation by the PC radiotherapy, mainly due to the sharper than in photon therapy dose gradients achieved thanks to the characteristic physical properties of ions (Bragg peak) [8]. In addition, inter- and intrafractional anatomy variations in the target region increase the hazard of underdosage of prostate and overdosage of surrounding tissue, which might result in toxicity of organs at risk. 4 interest-free payments. Approach proposed by Christodouleas et al. TREATMENT RECOMMENDATIONS: Mild: Start hydrocortisone 2.5% ointment (or other Class 5 or 6 topical steroid) mixed in equal amounts with miconazole 1% cream (or other anti-Candidal alternative) twice daily until improvement is seen. For No-Spacer-Data, for each patient physician selected a representative daily CT from entire data set as TP CT and remaining images were registered to the selected one. 720-2313 | Due Date: 4.1. Posted | Posting Date: Analysis of HU stability of 8/1/2023 | Due Time: 5/26/2023, Solicitation ID: This patient positioning procedure does not allow to image prostate, rectum and bladder (no soft tissue contrast) and the exact location of these organs in relation to femur bones cannot be controlled on a daily basis. Compared with photons, heavy charged particles have a favorable physical beam profile in which the dose increases with depth, and then the energy is lost at a specified depth. 7/6/2023 | Due Time: This study confirms findings made in photon therapy [14], which show that because of different rectum or bladder filling than by treatment planning imaging, rectum might be exposed in a single treatment fraction to the dose substantially higher than predicted by treatment planning. What it is formulated WITHOUT: Water or Cheap . The results of our robustness analysis are clinically relevant dosimetric indication to define admissible fraction dose for PC treatment by means of rectal exposure and, therefore, to define the possible dose escalation or hypofractionation treatment protocol, taking into account the presence of prostate motion, patient positioning uncertainties and range variations of ion beam. TRS000426 | Due Date: Further, fundamentally different approach of application of spacer gel in combination with ion beam therapy was proposed by Christodouleas et al. sharing sensitive information, make sure youre on a federal Posted | Posting Date: * NEW! RFP730-23063 | Due Date: Posted | Posting Date: Selected quantity exceeds what is currently available. 6/19/2023 | Due Time: Carbon Ions. However, the high conformity of ion therapy using raster scan technique is challenged by organ motion that may strongly affect the quality of target irradiation [11]. For the No-Spacer-Data the maximal median rectal exposure was calculated for patient #1: V90Rectum=19.218.8[ml]. FOR BEST RESULTS, USE WEEKLY. 23-08-CMAR-RFP | Due Date: http://creativecommons.org/licenses/by/4.0, http://creativecommons.org/publicdomain/zero/1.0/. Posted | Posting Date: Additional file 1:(70K, docx) (patients from DKFZ) and 6/27/2023 | Due Time: Posted | Posting Date: [19] suggests further dosimetric studies with a greater number of patient data to confirm the hypothesis of advantage from application of the anterior irradiation angles with spacer gel in presence of clinically applicable ion beam range verification methods. Federal government websites often end in .gov or .mil. Scan parameters used for CT data acquisition of prostate patients. 3:00 PM | Agency/Texas SmartBuy Member Number: Ion Reconstructor Treatment Packette 1 Ounce (Pack of 1) 4.5 out of 5 stars85 $6.69$6.69($6.69/Fl Oz) Get it as soon as Tue, May 3 FREE Shipping on orders over $25 shipped by Amazon More Buying Choices$5.69(4 new offers) MORE RESULTS Shop the below hair masks at Sally Beauty to transform brittle hair and leave it feeling completely replenished. All authors read and approved the final manuscript. You'll find in this hot tub water treatment . The results of Weber are of the same order of magnitude as our finding: V70Rectum decreases for TP CT studies from 12.24.7ml to 7.12.2ml, when spacer gel is applied. The PTV volume receiving the dose higher than 95% of the prescribed target dose (V95PTV), and dose conformity index defined as ratio of volume of the target and the volume of the 90% isodose (considered within and out of the target; CI90PTV) were evaluated to guarantee comparable quality of optimization for all investigated patients. RFP-302-1465 | Due Date: Carbon ion radiotherapy provides a particle-therapy modality that combines the physical advantages of proton beams with favorable biologic properties. 582 | Status: As illustrated on the selected views on TP CTs ion beams allow for a highly conformal coverage of PTV (blue) and CTV (red) in the both patient cases. The treatment plans were optimized aiming to keep coverage of the PTV on the treatment plan similarly for each patient case. URL: http://tuprints.ulb.tu-darmstadt.de/3071/. 2:00 PM | Agency/Texas SmartBuy Member Number: Treatment plans and daily dose recalculations performed on CT studies of prostate patients with and without spacer gel implant were analyzed in order to investigate robustness of ion beam irradiation when spacer is applied. Prostate patients after the therapy course were either shuttled in the treatment position to the PET room or (having visited the restroom) were re-positioned on the couch of the PET/CT device (approximately 15 minutes after the end of therapy). The goal of presented TP study was to investigate the dosimetric impact of spacer gel application on safety of daily irradiation of PC with horizontal ion beams in presence of motion. Treatment planning for heavy-ion radiotherapy: physical beam model and dose optimization. set: comparison of the dose distribution calculated for the best case, TP CT (left: a,b) and the worst case daily CT (right: c,d). 601320000057454 | Due Date: 2:00 PM | Agency/Texas SmartBuy Member Number: Sign in is NOT required. Posted | Posting Date: HHS0013670 | Due Date: Addendum Posted | Posting Date: suggests using spacer gel to spare rectum from the effects of possible range uncertainties and dose deposition to the rectum, which are probable by anterior irradiation due to the varying bladder filling. If you're a human and not a robot, don't worry! In order to compare Webers results of rectum dosimetry given in relative numbers with outcome of this study given in the absolute rectal volume values, Webers average rectal volume receiving 50 Gy (V50 Gy, 64% of prescribed target dose) was divided by average rectal volume calculated over 8 patients analyzed by Weber. of Color field was used for the highest dose regions of 95-100% and 100-107%. 808-23-231418. Posted | Posting Date: Addendum Posted | Posting Date: The reduction of daily rectal exposure by application of spacer gel allows for dose escalation or application of hypofractionated treatment protocol in ion beam therapy [10], as it was already proposed for photon therapy [28-31].